关于COVID-19疫苗副作用的长度随访研究:使用电话问卷方法
Krishna Priya Jakkula1, J Kishore2, Uma Maheswar Rao1
1Medicine, Lions Cancer Hospital, Visakhapatnam, IND.
Cureus
|July 23, 2024
概括
两种COVID-19疫苗Covishield和Covaxin显示出不同的副作用概况. 与Covishield相比,Covaxin感染较少,但注射部位疼痛较多,副作用的总体几率较高.
科学领域:
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 由于COVID-19大流行,疫苗的快速研发成为必要,导致对Covishield和Covaxin等疫苗的紧急使用授权.
- 尽管这些疫苗被广泛使用,但了解这些疫苗的比较安全性和副作用概况仍然至关重要.
研究的目的:
- 纵向评估和比较人口特征,副作用频率和严重程度.
- 调查疫苗类型 (Covishield vs. Covaxin) 和人口因素与副作用相关的关联.
主要方法:
- 一个电话问卷收集了2021年1月至2022年1月期间接种疫苗的个人数据.
- 使用后勤回归分析来确定疫苗类型,人口统计和副作用可能性之间的关联.
主要成果:
- 与Covishield接种者相比,Covaxin接种者报告的轻度类似流感的疾病和接种后感染率较低.
- 接种Covaxin的患者在注射部位出现了更多的疼痛;然而,Covaxin的副作用的总体几率明显高于Covaxin (OR = 1.687,p < 0.001).
- 年龄,性别和种族与经历副作用的可能性有显著的关联.
结论:
- 科维希尔德和Covaxin具有不同的安全性和耐受性.
- 持续的疫苗安全监测对于为公共卫生政策和疫苗接种策略提供信息至关重要.
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