相关实验视频

Updated: Jun 20, 2025

A "Dual-Addition" Calcium Fluorescence Assay for the High-Throughput Screening of Recombinant G Protein-Coupled Receptors
08:46

A "Dual-Addition" Calcium Fluorescence Assay for the High-Throughput Screening of Recombinant G Protein-Coupled Receptors

Published on: December 2, 2022

2.2K

在两个单基因物种的基因组中识别潜在的药物标

V H Caña-Bozada1, C Ovando-Vázquez2,3, L C Flores-Méndez1,4

  • 1Centro de Investigación en Alimentación y Desarrollo, A.C., Mazatlán, Sinaloa 82112, Mexico.

Helminthologia
|July 23, 2024
PubMed
概括

研究人员鉴定和分类了单种寄生虫Rhabdosynochus viridisi和Scutogyrus longicornis中的蛋白激酶. 他们确定了潜在的单一性药物标 (MDT),并建议现有药物作为抗寄生虫剂重新使用.

关键词:
达克提洛基瑞科的动物.这是一个Diplectanidae.爱尔哥他胺是一种水产养殖的水产养殖鱼类寄生虫 鱼类寄生虫基因组学就是基因组学.

更多相关视频

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays13:22

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Published on: October 23, 2019

7.9K
Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein11:23

Characterization at the Molecular Level using Robust Biochemical Approaches of a New Kinase Protein

Published on: June 30, 2019

6.2K

相关概念视频

Targets for Drug Action: Overview01:26

Targets for Drug Action: Overview

Drugs target macromolecules to modify ongoing cellular processes. Primary drug targets include receptors, ion channels, transporters, and enzymes.
Receptors are either membrane-spanning or intracellular proteins, which upon binding a ligand, get activated and transmit the signal downstream to elicit a response. Drugs bind receptors, either mimicking the action of endogenous ligands or blocking the receptor activity to bring about a modified response. Nearly 35% of approved drugs target the G...
6.1K
Transducer Mechanism: Enzyme-Linked Receptors01:27

Transducer Mechanism: Enzyme-Linked Receptors

Enzyme-linked receptors are cell-surface receptors acting as an enzyme or associating with an enzyme intracellularly. They make excellent drug targets. Drugs can bind to the extracellular ligand-binding domain or directly affect their enzymatic domain and alter their activity.
Major types that are helpful drug targets include:
2.4K