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[在II型原蛋白诱导性关节炎的雌性大鼠中,托利德对生殖毒性的影响]

Yuan-Fang Fan1, Xiao-Hui Su1, Ying Xu1

  • 1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
|July 23, 2024
PubMed
概括

托利 (TP) 在雌性大鼠中没有引起显著的生殖损伤,剂量低于临床相当量的两倍. 然而,TP通过抑制TGFβ3/Smad3/SF-1通路促进了卵巢细胞亡和生殖毒性.

关键词:
雌性大鼠患有原诱导的关节炎有毒作用的机制有毒作用的机制.卵巢功能 卵巢功能毒性的毒性 毒性的毒性三托利化物是什么

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