阻塞性睡眠呼吸暂停的预防药物 - 一个系统的审查和呼吁采取行动
Eduardo J Correa1, Diego M Conti2, David Gozal3
1Otorhinolaryngology Department, Hospital La Linea de la Concepción, Cadiz España.
Sleep
|July 23, 2024
概括
这一系统性审查强调了阻塞性睡眠呼吸暂停 (OSA) 研究中的重大差距,与治疗相比,预防的研究很少. 优先考虑OSA预防策略对于公共卫生至关重要.
科学领域:
- 睡眠医学 睡眠医学
- 公共卫生 公共卫生
- 预防医学 预防医学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍存在的疾病,具有重大健康后果.
- 在OSA预防和治疗之间,研究工作存在显著的不平衡.
研究的目的:
- 系统地审查阻塞性睡眠呼吸暂停 (OSA) 的可修改风险因素.
- 分析现有的文献,专注于预防OSA.
主要方法:
- 在Cochrane,EMBASE,MEDLINE,PubMed和LILACS进行了全面的文献搜索.
- 引用文章的交叉引用和部分灰色文献搜索通过谷歌学者.
- 使用诊断准确性研究的14项质量评估工具对包括的研究进行质量评估.
主要成果:
- 最初的搜索结果是720篇关于OSA风险因素,预防和生活方式改变的出版物.
- 只有四篇论文满足了关于OSA预防的系统性审查的纳入标准.
- 发现了23674篇关于OSA治疗方法的文章,形成了鲜明的对比,这表明研究失衡.
结论:
- 倡导OSA预防是必不可少的,尽管经济利益有利于诊断和治疗.
- 多维预防策略,公众教育和早期诊断OSA至关重要.
- 建议全球加大对OSA预防的关注,以减轻疾病后果.
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