血清酸盐,,和大动脉硬化症之间的关联:一种倾向性得分匹配的病例控制研究
Jing Tao1,2, Juan Wang1,2, Hui Peng1,2
1Xinjiang Key Laboratory of Cardiovascular Homeostasis and Regeneration Research, Urumqi, Xinjiang, China.
Acta cardiologica
|July 23, 2024
概括
血清可能会防止大动脉硬化,而异常的血清水平会增加风险. 这些发现突出了心血管疾病风险预测和早期干预策略的潜在生物标志物.
科学领域:
- 心血管医学 心血管医学
- 临床生物化学 临床生物化学
- 营养科学 营养科学
背景情况:
- 大动脉硬化与心血管风险增加有关.
- 血清微量元素与大动脉硬化有关.
- 了解风险因素对于预防心血管疾病至关重要.
研究的目的:
- 调查血清和水平与大动脉硬化症之间的关联.
- 探索血清微量营养素作为心血管疾病风险指标的潜力.
主要方法:
- 从2019年至2021年对3066名患者 (1,533名有大动脉硬化症,1,533名对照) 的回顾性研究.
- 倾向性得分匹配 (1:1) 来比较患者组.
- 后勤回归分析以确定影响因素.
主要成果:
- 血清与大动脉硬化风险降低有关 (OR:0.346).
- 低血清水平和高血清水平都与增加风险相关 (OR:7.022).
- 与较高血清水平 (p < 0.05) 观察到明显较低的风险.
结论:
- 血清可能对大动脉硬化产生保护作用.
- 异常的血清水平 (低和高) 是大动脉硬化症的危险因素.
- 血清和需要进一步研究心血管疾病风险预测和预防.
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