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通过商业分子测定方法错过了利芬素和异化物耐药性

L Richards1, F Ismail2, J Nel3

  • 1Division of Infectious Diseases, Department of Internal Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. lauren.richards@wits.ac.za.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde
|July 23, 2024
PubMed
概括

早期检测耐药结核病 (TB) 是至关重要的. 一个案例研究强调了分子测试如何错过多药耐药结核病,强调了在特定场景中需要表型测试.

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MALDI-TOF MS has transformed clinical microbiology by offering a rapid and reliable method for pathogen identification. The traditional approach to microbial identification typically involves time-consuming culture techniques and biochemical tests, which can delay the initiation of appropriate antimicrobial therapy. MALDI-TOF MS avoids these delays by using characteristic ribosomal protein mass patterns of microbial cells, enabling accurate species-level identification within minutes.Principle...