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射频废除用于治疗良性甲状腺结节:10年的经验

Sang Ik Park^1,2, Jung Hwan Baek¹, Da Hyun Lee^1,3

¹Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Thyroid : official journal of the American Thyroid Association

|July 23, 2024

概括

射频除 (RFA) 有效地治疗良性甲状腺结节,显示高体积减少和长期安全. 然而,由于结节可能重新生长,并且在某些情况下需要推迟手术,因此定期的随访至关重要.

科学领域:

内分泌学在内分泌学.
干预性放射学干预性放射学
在瘤学瘤学.

背景情况:

射频除 (RFA) 是一种治疗良性甲状腺结节的方法.
关于RFA疗效的长期数据有限,包括结节的再生和并发症.
了解这些因素对于患者管理和治疗规划至关重要.

研究的目的:

为了评估放射频移除 (RFA) 对良性甲状腺结节的长期结果.
评估结节的再生率,延迟手术的必要性和并发症发生率.
为了确定与RFA后结节再生长相关的风险因素.

主要方法:

对421名患有456例良性甲状腺结节的患者进行了回顾性研究,这些患者接受了RFA治疗 (2007年3月至2010年12月).
长期跟踪至2022年8月,计算体积减小比率 (VRR) 并评估再生,延迟手术和并发症.
卡普兰-梅尔分析累积再生发病率和考克斯回归用于风险因素识别.

主要成果:

观察到高平均VRR:81%在2年,90%在5年和94%在≥10年.
在12%的结节中发生了整体再生;较大的初始体积 (≥20毫升) 与更高的再生风险有关.
在6%的患者中进行了延迟手术;整体并发症率为2.4%,没有长期问题.

结论:

射频除 (RFA) 是一种安全有效的治疗良性甲状腺结节的方法,可以实现显著的长期体积减少.
定期长期随访至关重要,以监测结节的再生和可能需要推迟手术的可能性.
最初的结节体积是RFA后复发风险的重要预测指标.

关键词:

无线电频率剥离方式甲状腺结节甲状腺结节

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