用两种不同的自动化抗微生物敏感性测试系统进行赛福西丁查试验的性能评估:一项比较性研究
Ismail Yuceel-Timur1, Cherilyn D Garner2, Simone Franklin2
1Global Medical Affairs, bioMérieux, Lyon, France.
Microbiology spectrum
|July 23, 2024
概括
这项研究评估了自动化系统,用于检测Staphylococcus中的β-乳酸盐耐药性. 维特克2和BD城系统显示出高准确度,特别是当结合cefoxitin和oxacillin测试时,可靠的患者护理.
科学领域:
- 临床微生物学 临床微生物学
- 抗微生物耐药性 抗微生物耐药性
- 诊断技术 诊断技术的使用
背景情况:
- 精确检测由mecA和mecC基因介导的β-乳抗性,对于有效的患者管理至关重要.
- 自动化抗微生物敏感性测试 (AST) 系统被广泛用于快速敏感性结果.
研究的目的:
- 为了比较Vitek 2和BD Phoenix自动化系统在检测mecA/mecC介导β-乳抗性的性能.
- 与参考方法和BD Phoenix系统相比,对Vitek 2上的新的cefoxitin查测试进行评估.
主要方法:
- 评估了250个葡萄球菌分离物 (120个meca阳性,10个meca阳性,120个负).
- 在Vitek 2和BD Phoenix上进行了塞福西丁选和西林测试,与盘扩散和微稀释参考方法进行了比较.
- 使用PCR来确认mecA和mecC基因.
主要成果:
- 维特克2 素镜:100%的灵敏度,98%的特异性与参考相比.
- BD城素镜:灵敏度为84%,特异性为100%与参考相比.
- 结合的塞福西和西林试验提高了的灵敏度至100%,特异性没有变化.
结论:
- 维特克2 cefoxitin 屏幕在检测mecA/mecC介导的耐药性方面表现出高灵敏度.
- 维特克2和BD Phoenix在使用素和素测试的组合时都获得了高性能.
- 这些发现支持在临床环境中可靠使用这些自动化系统.
关键词:
在BDD城.在MRSA中,MRSA可能是MRSA.城是什么意思 城是什么意思葡萄球菌 spp. 葡萄球菌 spp.维特克 2 维特克 2塞福西丁 (oxsf02n) 是一种一个Cefoxitin屏幕.耐甲西林的葡萄球菌 spp.牛氧素的使用方法更多相关视频
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