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Updated: Jun 19, 2025

Humanized Mouse Model to Study Bacterial Infections Targeting the Microvasculature
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尼塞里亚粘附素A (NadA) 结合人类的Siglec-5和Siglec-14具有很高的亲和力,并促进细菌的粘附/入侵

Barbara Benucci1, Zaira Spinello1, Valeria Calvaresi1,2

  • 1GSK, Siena, Italy.

mBio
|July 23, 2024
PubMed
概括

尼塞里亚粘附素A (NadA) 与Siglec-5和Siglec-14受体结合,对于脑膜炎球菌的粘附和入侵至关重要. 这一发现有助于人们更好地了解Neisseria meningitidis在感染期间如何向免疫细胞.

关键词:
纳达A受体是一种NADA受体.脑膜炎的尼塞利亚菌.在A (NadA) 中需要连续粘合西格莱克 - 14 号西格莱克-5 号西格莱克-9号

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