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Updated: Jun 19, 2025

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ω-Grammotoxin-SIA 抑制了电压关闭的 Na+ 通道电流

Rita de Cássia Collaço1, Filip Van Petegem2,3, Frank Bosmans1,4

  • 1Department of Basic and Applied Medical Sciences, Molecular Physiology and Neurophysics Group, Ghent University, Ghent, Belgium.

The Journal of general physiology
|July 23, 2024
PubMed
概括

tarantula 毒液中的 ω-Grammotoxin-SIA (GrTX-SIA) 抑制了电压接 (NaV) 通道,特别是 NaV1.6.6. 这种酸向 NaV 通道中的保留电压感应域,作为广泛的离子通道修饰器.

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