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为旨在改善初级保健中老年人适当的多药学试验的核心结果集选择结果测量仪器:德尔菲共识研究
Mubarak N Alqahtani1, Heather E Barry1, Carmel M Hughes2
1Primary Care Research Group, School of Pharmacy, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7BL, UK.
International journal of clinical pharmacy
|July 23, 2024
概括
研究人员选择了对老年人多药核心结果集的结果测量仪器. 对于严重的药物不良反应,死亡率和跌倒,商定了三个工具.
科学领域:
- 老年医学 老年医学
- 药理学 药理学是指药理学的学科.
- 医疗保健服务研究 医疗服务研究
背景情况:
- 对于初级保健中的多药学,有一个核心结果集 (COS),但缺乏定义的结果测量仪器 (OMI).
- 衡量多药学结果对于老年患者的适当护理至关重要.
研究的目的:
- 在初级保健中选择合适的OMI用于多药房COS的老年患者.
- 建立关于可靠仪器的共识,以衡量多药的主要结果.
主要方法:
- 通过Cochrane审查确定了OMI,并使用COSMIN指南进行评估.
- 为了达成共识,进行了两轮的德尔菲会议,涉及老年初级保健利益相关者.
- 需要达成共识>=70%同意和<=15%不同意.
主要成果:
- 七个OMI符合最低质量要求.
- 50名受访者完成了德尔菲演习.
- 在对严重药物不良反应 (ADRs),死亡率和跌倒的OMI达成共识.
结论:
- 对于多药COS结果的一个子集,OMI成功地被选择.
- 需要进一步的研究来确定OMI对药物的适当性,副作用,生活质量和治疗方案的复杂性.
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