"狼不是我,我有狼":利用以患者为中心的采访来了解药物不服药
Christopher A Macko1, Roger Santos2, Nirmala D Ramalingam3
1Department of Medicine, Kaiser Permanente Oakland Medical Center, Oakland, CA, USA.
The Permanente journal
|July 23, 2024
概括
大多数接受mycophenolate mofetil (MMF) 治疗的狼性炎患者都坚持治疗. 遗忘是不坚持患者的关键障碍,突出了在狼性炎管理中需要坚持支持策略的需要.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 类风湿病学 类风湿病学
- 药理学 药理学是指药理学的学科.
背景情况:
- 狼性炎 (LN) 是系统性红斑狼的一种严重并发症,显著增加了发病率和死亡率.
- 在LN患者中,不良的药物坚持与负面的临床结果和疾病进展有关.
研究的目的:
- 为了研究狼性炎患者中甲 (MMF) 的药物坚持率.
- 确定导致MMF治疗的LN患者不坚持治疗的因素.
主要方法:
- 在一个综合卫生系统中,对LN患者的MMF处方进行了回顾性分析.
- 对患者进行采访,以探讨低服药坚持的原因.
- 遵守率定义为覆盖日数的比例> 80%.
主要成果:
- 69%接受MMF的LN患者表现出药物坚持 (>80%的日数覆盖).
- 不遵守的关键原因包括遗忘 (57%),不完整的实验室工作 (28%) 和药物成本 (14%).
- 没有患者将药物副作用作为不服药的原因.
结论:
- 在研究的卫生系统内,在MMF的LN患者中观察到高的药物坚持率.
- 忘记症对不坚持的患者来说是一个重大挑战.
- 提供方便的补充和实验室服务的综合卫生系统可能会提高LN药物坚持.
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