澳大利亚昆士兰州的结核性硬化综合体儿童的结果是否发生了变化?
Melissa Braun1, Kate Riney2,3
1Metro South Addiction and Mental Health Service, Princess Alexandra Hospital, Brisbane, Queensland, Australia.
Epilepsia
|July 23, 2024
概括
结核性硬化综合体 (TSC) 中仍然很常见,尽管早期诊断. 然而,护理方面的进步提高了的缓解率,为受影响的儿童及其家人提供了希望.
科学领域:
- 儿科神经学 儿科神经学
- 遗传学 遗传学 是一个
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 是结核性硬化综合体 (TSC) 的主要表现.
- 最近TSC医疗保健的进步需要对结局的最新理解.
- 这项研究调查了过去十年中儿科TSC患者发病表现和治疗的变化.
研究的目的:
- 评估结核性硬化综合体 (TSC) 的儿童的结果是否发生变化.
- 为了比较2012年以前和之后出生的TSC患者的诊断和治疗趋势.
- 为新诊断的儿科TSC患者的辅导父母提供最新信息.
主要方法:
- 在澳大利亚昆士兰州诊断出TSC的儿科患者的回顾性图表审查.
- 提取有关结局和TSC诊断时间的数据.
- 在2012年之前出生的人群和2012年或之后出生的人群之间的结果比较.
主要成果:
- 在TSC中的频率 (85%) 没有变化,但诊断越来越多的是产前和早期.
- 虽然起初婴儿 (IS) 的频率较低,但晚发IS与缓解率较低相关.
- 尽管治疗耐药性的发病率很高,但66%的患者实现了缓解,通常是通过手术或年龄.
结论:
- 早些时候的TSC诊断并没有减少的患病率,但改变了诊断时间.
- 改进的管理策略有助于提高儿科TSC的缓解率.
- 更新的数据对于有关TSC相关的知情家长咨询至关重要.
更多相关视频
06:04Author Spotlight: Studying Clinical Characters and Epilepsy Outcomes After Frontal Disconnection in Patients with MOGHE
Published on: August 16, 2024
808
10:22Interictal High Frequency Oscillations Detected with Simultaneous Magnetoencephalography and Electroencephalography as Biomarker of Pediatric Epilepsy
Published on: December 6, 2016
20.3K
相关概念视频
01:13Seizures: Classification
326
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
326
01:24Arteries of the Lower Limbs
182
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
182
01:30Electroconvulsive Therapy
30
Electroconvulsive therapy (ECT), or shock therapy, remains a critical biomedical intervention for severe, treatment-resistant depression. While its origins can be traced back to Hippocrates' observations that malaria-induced convulsions alleviated mental illness, modern ECT has evolved significantly from its earlier, more primitive applications. First introduced in 1938 by Ugo Cerletti and his colleagues, ECT involves inducing controlled seizures using electrical currents. In its early...
30