在美国康涅狄格州,孕期住宅暴露和产期低出生体重之间的关联
Seulkee Heo1, Longxiang Li2, Ji-Young Son1
1From the School of the Environment, Yale University, CT.
Epidemiology (Cambridge, Mass.)
|July 23, 2024
概括
孕期暴露在地下室中,即使低于EPA指南,也与低出生体重的风险增加有关. 这些发现凸显了怀孕期间暴露对婴儿健康的潜在担忧.
科学领域:
- 环境健康 环境健康
- 围产期流行病学 围产期流行病学
- 公共卫生 公共卫生
背景情况:
- 孕期暴露于辐射可能会损害胎儿的发育.
- 关于怀孕期间暴露于和产期低出生体重的证据有限.
研究的目的:
- 探索妊娠期暴露和出生时低体重之间的关联.
- 为了调查低于美国环保署指南的水平的风险.
主要方法:
- 检查了来自康涅狄格州68,159个单子全产婴儿 (2016-2018) 的数据.
- 利用时空模型来估计怀孕期间的暴露水平.
- 采用后勤回归来评估四个暴露四分位数中低出生体重的几率比率.
主要成果:
- 底层水平低于EPA指南 (4 pCi/L).
- 在第一 trimester (ORs 1.22-1.26) 期间,在较高的底层暴露四分位数中观察到较低出生体重的几率增加.
- 较低社会经济地位的参与者和城市地区的参与者发现风险更高.
结论:
- 低出生体重的风险增加与地下室暴露的增加有关.
- 研究结果表明,即使水平低于国家指南,也可能对婴儿健康产生潜在影响.
- 结果强调在建筑和公共卫生战略中考虑减轻的重要性.
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