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Updated: Jun 19, 2025

Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions
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Bioinformatics Resources for the Study of Glycan-Mediated Protein Interactions

Published on: January 20, 2022

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作为指导选择生物活性小分子的工具的N-糖化诱导病态蛋白质构造

Andrea Magni1, Cristiano Sciva1,2, Matteo Castelli1

  • 1Department of Chemistry, University of Pavia, 27100, Pavia, Italy.

Chemistry (Weinheim an der Bergstrasse, Germany)
|July 23, 2024
PubMed
概括

针对Grp94 (热冲击蛋白90) 中的异常N-糖化,可以破坏疾病的发展路径. 这项研究区分了针对特定,致病性Grp94形状的配体,帮助药物设计.

关键词:
陪伴者 (Chaperones) 是指一个陪伴者.药物设计 药物设计分子动力学分子动力学后翻译修改后的修改.

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