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Updated: Jun 19, 2025

Selection of Transporter-Targeted Inhibitory Nanobodies by Solid-Supported-Membrane SSM-Based Electrophysiology
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哺乳动物质子合载体的机制

Simon M Lichtinger1,2, Joanne L Parker1,2, Simon Newstead1,2

  • 1Structural Bioinformatics and Computational Biochemistry, Department of Biochemistry, University of Oxford, Oxford, United Kingdom.

eLife
|July 23, 2024
PubMed
概括

质子合的寡转运体 (POT) 通过合质子和结合来促进药物运输. 分子动力学模拟揭示了驱动SLC15A2运输的关键质子化步骤,改善了药物的生物可用性.

关键词:
这是一种计算式计算.自由的能源自由的能源.分子生物物理学分子生物物理学质子化 质子化 质子化鼠标 鼠标 鼠标 鼠标 鼠标溶解物载体蛋白质是一种溶解物载体蛋白质.结构生物学结构生物学

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