前腔室空气气泡动力学与大气压的下降
Ruth Donner1, Julia Aschauer, Gerald Schmidinger
1Department of Ophthalmology and Optometry, Medical University of Vienna, Vienna, Austria.
降低气压显著增加眼内压力 (IOP) 在眼睛与较大的前腔室气泡. 较小的气泡可以在适度的高度变化中安全旅行.
科学领域:
- 眼科医生 眼科 眼科
- 生物医学工程 生物医学工程
- 生理学 生理学 生理学
背景情况:
- 室内气泡在眼科手术中使用.
- 气压的变化可以影响眼内压力 (IOP).
研究的目的:
- 评估气压下降对室内气泡大小和眼内压力 (IOP) 的影响.
- 为了评估前腔室空气填充在降低大气压下对IOP的影响.
主要方法:
- 人体捐赠者的眼睛 (n=36) 在前腔中充满了30%,50%或90%的空气.
- 眼睛受到大气压降至750hPa (海拔2400米) 的下降.
- 监测室内泡大小和IOP使用前段光学连贯性断层扫描和连续IOP测量.
主要成果:
- 眼睛有30%的空气填充显示IOP增加到42.08mm Hg在750hPa.
- 眼睛有50%的空气填充经历了IOP增加到63.33mm Hg在750hPa.
- 90%空气填充的眼睛在850hPa时达到平均IOP113.42mm Hg,阻止了进一步的压力降低.
结论:
- 前腔的大气泡会导致严重的内压增加随着大气压力下降.
- 小到中等的气泡可能允许在适度的高度变化中旅行,而不会显著增加IOP.
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