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对于镜像查的互白素-6的化学合成

Keisuke Aoki1,2, Kayuu Maeda3, Shinsuke Inuki1

  • 1Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan.

Bioconjugate chemistry
|July 23, 2024
PubMed
概括

研究人员通过化学合成了INTERLEUKIN-6 (IL-6) 和它的镜像d-IL-6,使得新型IL-6抑制剂的开发成为可能. 这一突破为减少免疫副作用的炎症性疾病提供了潜在的治疗方法.

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相关概念视频

Stereoisomerism02:52

Stereoisomerism

Isomerism in Complexes
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...