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Updated: Jun 19, 2025

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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Published on: January 20, 2019

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独特的表观基因组景观是组织特异性记忆T细胞分化的基础

Frank A Buquicchio1, Raissa Fonseca2, Patrick K Yan3

  • 1Department of Pathology, Stanford University, Stanford, CA 94305, USA; Program in Immunology, Stanford University, Stanford, CA 94304, USA; Gladstone-UCSF Institute of Genomic Immunology, San Francisco, CA 94158, USA.

Immunity
|July 23, 2024
PubMed
概括

组织内存T (TRM) 细胞和循环记忆T (TCIRC) 细胞表现出不同的表观遗传特征. 这项研究揭示了关键的调节器和表观遗传特征,这些特征定义了TRM细胞在各器官的发育和功能.

关键词:
染色质可访问性 染色质可访问性发展发展发展发展发展.表观遗传学是指表观遗传学.监管要素 监管元素 监管元素单细胞基因组学 单细胞基因组学组织免疫 组织免疫组织内存T细胞 组织内存T细胞转录调节器是指转录调节器.

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