在识别微妙月经障碍的2步和3步方法之间达成协议
Dionne A Noordhof1, Madison Y Taylor2, Virginia De Martin Topranin1,3
1Department of Neuromedicine and Movement Science, Center for Elite Sports Research, Norwegian University of Science and Technology, Trondheim, Norway.
概括
检测微妙月经障碍 (SMD) 的两步方法与三步方法基本一致,但可能无法检测到某些病例. 虽然它证实了检测到的SMD,但当没有发现时,它不能排除它们的缺席.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 运动医学运动医学
- 妇科 妇科医生 妇科
背景情况:
- 微妙的月经障碍 (SMD) 需要准确的识别.
- 建议使用三步方法 (日历,尿液排卵测试,血清采样),但要求很高.
- 一种不那么密集的两步方法 (日历,尿液排卵测试) 是一个潜在的替代方案.
研究的目的:
- 评估检测SMD的2步和3步方法之间的一致性.
- 为了确定二步方法的可靠性,作为三步方法的替代品.
主要方法:
- 评估了59名运动员的98个月经周期 (MCs),使用两步和三步方法.
- 根据黄体阶段的长度,孕激素水平和排卵状态来定义SMD.
- 使用McNemar测试和Cohen kappa (κ) 进行方法协议分析.
主要成果:
- 在两步和三步方法之间发现了实质性的一致性 (κ = .72).
- 两步方法表现出系统偏差,未能检测到38.9%的SMD.
- 两步方法正确识别了100%的非SMD循环,但只有61.1%的SMD循环.
结论:
- 经由两步方法发现的被扰乱的月经周期可能是有效的SMD.
- 由于这两步方法的检测不足,因此无法确定SMD的不存在.
- 对两步方法的临床解释需要意识到其在检测所有SMD方面的局限性.
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