医院供应药房中的囊片包装机器的清洁验证
Dominic Fenske1, Lilly Zerrenner1, Stephanie Zergiebel2
1Hospital Pharmacy, HELIOS Klinikum Erfurt, Erfurt, Germany.
概括
一种新的UV-Vis光谱法为HPLC提供了一种更快,更便宜,同样可靠的替代方案,用于清洁片机器的验证. 这一创新对于确保医院药房的质量保证的患者护理至关重要.
科学领域:
- 制药技术 制药技术 制药技术
- 分析化学 分析化学
- 质量保证 质量保证 质量保证
背景情况:
- 全球范围内,医院药房越来越多地采用单剂量囊泡.
- 确保质量保证的病人护理需要经过验证的清洁流程来清洁气囊机.
- 高性能液体染色学 (HPLC) 是有效的,但对于清洁验证来说是昂贵的.
研究的目的:
- 开发一种新的,快速的,经济高效的分析方法来验证囊泡机清洗.
- 为此目的,建立UV-Vis光谱作为HPLC的可行替代方案.
主要方法:
- 标记物质 (甲米和) 被包装成囊泡.
- 囊泡机被清洗,测试片被包装在清洗前和清洗后.
- 使用UV-Vis光谱学评估了污染.
主要成果:
- 紫外线-Vis光谱学在清洁验证方面表现出优于HPLC的优势.
- 这种方法比HPLC快得多,更经济.
- 它需要更少的设备和人员努力,同时保持可靠性和灵敏性.
结论:
- 紫外线-Vis光谱法是第一个适用于清洁验证囊泡机的创新方法.
- 这些机器的清洁验证是强制性的照顾义务.
- 这种方法支持在医疗保健中日益使用单剂量囊泡的方法.
相关概念视频
Cleaning, Sterilization, and Disinfection
6.6K
Cleaning, disinfection, and sterilization are the methods that help to break the infection chain and prevent disease.
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
Cleaning
The cleaning process usually involves using water with detergents or enzymatic cleaner and removing foreign material from objects and surfaces, including organic material such as body fluids or inorganic material like soil. Cleaning is performed before high-level disinfection and sterilization because foreign materials on the cover of the devices interfere with process...
6.6K
Handwashing I: Introduction and Types of Equipment
4.1K
Handwashing is hand hygiene with plain or antimicrobial soap and water to physically remove dirt, organic material, and microorganisms. However, it may not kill all microorganisms. The handwashing procedure requires a hand wash basin, liquid soap, paper towels, a domestic waste bin, and disposable nail cleaner as optional equipment.
Hand wash basins in clinical areas should have faucets that can be turned on and off without using the hands; that is, they should be non-touch or lever-operated....
Hand wash basins in clinical areas should have faucets that can be turned on and off without using the hands; that is, they should be non-touch or lever-operated....
4.1K
Methods of Sterilization II: Chemical Methods
6.2K
In healthcare, the chemical method of sterilization uses chemical sterilants to treat surgical instruments and medical supplies to help prevent the transmission of infectious pathogens to patients. Due to heat sensitivity, most medical supplies and equipment should not be exposed to high temperatures. These parts include rubber, plastic, glass, and other similar elements.
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
Using chemical sterilization rather than heat to clean out equipment is recommended. It eradicates and removes all bacteria,...
6.2K
Standard Precaution
1.9K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
1.9K


