安全和遵守药物和瘤学自我护理建议 (SAMSON):试点随机对照试验协议
Thu Ha Dang1,2,3, Nilmini Wickramasinghe4,5,6, Prem Prakash Jayaraman7
1Department of Psychological Sciences, School of Health Sciences, Swinburne University of Technology, Hawthorn, Victoria, Australia thuhadang@swin.edu.au.
BMJ open
|July 23, 2024
概括
这项试点研究评估了SAMSON数字解决方案,以改善口服抗癌药物的坚持. 该试验评估了其可行性和可接受性,以支持癌症患者遵守药物治疗.
科学领域:
- 在瘤学瘤学.
- 数字健康数字健康
- 临床试验 临床试验
背景情况:
- 口服抗癌药物 (OAMs) 存在影响治疗疗效和毒性的坚持挑战.
- 移动电话干预提供了一个潜在的解决方案,以支持OAM在家中的坚持.
- 数字干预在瘤学药物坚持方面有效性的证据有限.
研究的目的:
- 评估新型数字SAMSON解决方案的可接受性和可行性.
- 评估SAMSON在改善癌症患者药物坚持 (MA) 中的潜在疗效.
- 为未来全面随机对照试验 (RCT) 提供基础.
主要方法:
- 一项为期12周的双臂试验RCT,涉及50名患有血液,肺或黑色素瘤癌症的成年人.
- 参与者随机 (1:1) 分给SAMSON数字干预或常规护理.
- 主要结局:SAMSON的可接受性和可行性;次要结局:MA,毒性自我管理,焦虑,抑郁,生活质量.
主要成果:
- 本节不适用,因为这项研究是试点试验,结果正在等待.
结论:
- 萨姆森试验RCT将确定一种新的数字解决方案的可行性和可接受性,以改善癌症患者的药物服药.
- 结果将为未来的大规模RCT的设计提供信息,用于瘤学中的数字健康干预.
相关概念视频
Nursing Ethical Principles II
942
Ethical principles are essential in guiding nurses to fulfill their responsibilities, focusing on the quality of nursing care and decision-making. These principles, including autonomy, beneficence, non-maleficence, justice, and fidelity, shape the ethical framework within healthcare settings.
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
Consider the following scenario, which illustrates how these principles are applied in the care of Mr. John, a fifty-year-old teacher diagnosed with metastatic liver cancer.
Initially, Mr. John's...
942
Drug Therapy
41
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
41
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
125
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
125
Cancer Survival Analysis
336
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
336
Clinical Trials
6.6K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
There are four phases in a clinical trial. A phase one...
6.6K
Combination Therapies and Personalized Medicine
4.9K
Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
4.9K


