国际空间站探索任务规划表格的过期分析
Thomas E Diaz1,2, Emma C Ives1, Diana I Lazare3
1University of North Carolina at Chapel Hill Eshelman School of Pharmacy, Chapel Hill, NC, USA.
NPJ microgravity
|July 23, 2024
概括
国际空间站 (ISS) 上的许多药物在地球上的保质期很短,分析的91种药物中有54种在36个月内过期. 这给长期太空任务带来了挑战.
科学领域:
- 太空医学 太空医学
- 制药科学 制药科学 制药科学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在长时间太空飞行期间保持机组人员的健康需要有效的药物治疗.
- 之前的研究已经评估了选择国际空间站 (ISS) 药物的稳定性和有效性.
研究的目的:
- 对2023年国际空间站完整药物表单预计的陆地保质期进行全面分析.
- 为未来的勘探任务提供药品供应战略的信息.
主要方法:
- 利用来自4个国际药物注册局的数据来确定保质期信息.
- 分析了2023年国际空间站药物表,包括106种不同的药物.
主要成果:
- 在106种ISS药物中,91种 (86%) 的保质期数据是可访问的.
- 在这些药物中,54种药物在原始包装中估计的陆地保质期为36个月或更短.
- 14种药物预计将在不到24个月的时间内到期.
结论:
- 许多国际空间站药物的有限保质期对延长太空探索任务构成重大挑战.
- 需要运营策略来优化治疗结果,并减轻与太空中药物到期相关的风险.
- 延长药物的有效期或接受使用过期药物的风险是任务规划人员的关键考虑因素.
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