一项前性队列研究评估了萨科佩尼亚对持续门诊腹腔透析患者住院治疗的影响
Lailiang Wang1, Beixia Zhu1, Congping Xue1
1Department of Nephrology, Ningbo NO.2 Hospital, Ningbo, Zhejiang, China.
Scientific reports
|July 23, 2024
概括
皮症显著增加了中国患者的住院风险,这些患者接受了持续的门诊腹膜透析 (CAPD). 对这种人群来说,早期发现和治疗肉症至关重要,以减少住院患者.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 老年病的医生 老年病的医生
- 公共卫生 公共卫生
背景情况:
- 关于在透析患者中与住院治疗相关的萨尔科佩尼亚相关性,存在不确定的数据.
- 骨肌肉质量和强度的逐渐丧失,即萨尔科佩尼亚,在慢性脏疾病中很普遍.
- 持续的门诊腹膜透析 (CAPD) 患者代表了一个脆弱的人群,需要集中健康评估.
研究的目的:
- 调查中国CAPD患者的萨尔科佩尼亚和全因住院之间的关联.
- 根据使用已确定的诊断标准,根据肉症状态确定住院的风险.
主要方法:
- 对220名中国CAPD患者进行前性队列研究,随访48周.
- 根据2019年亚洲肉病工作组 (AWGS 2019) 标准进行的肉病诊断.
- 多变量逻辑回归和相对风险 (RR) 分析以评估住院风险.
主要成果:
- 麻症的患病率为54.1% (119/220),严重的麻症为28.2% (62/220).
- 住院治疗发生在51.4%的参与者中,65.5%的萨尔科佩尼亚组与非萨尔科佩尼亚组的34.7%相比 (RR=1.90).
- 麻症 (OR=3.21),非严重的麻症 (OR=2.84),以及严重的麻症 (OR=3.66) 与住院治疗有显著的关联.
结论:
- 萨科佩尼亚是中国CAPD患者住院治疗的重要独立风险因素.
- 2019年AWGS标准有效识别了高风险患者.
- 在CAPD患者中监测和管理肉类是减少住院率的关键.
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