健康饮食指数和卵巢储备减少的风险:一个病例对照研究
Hatav Ghasemi-Tehrani1, Gholamreza Askari2, Fatemeh Zahra Allameh3
1Reproductive Sciences and Sexual Health Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Scientific reports
|July 23, 2024
概括
坚持健康饮食指数 (HEI-2015) 可能会降低卵巢储量减少 (DOR) 的风险. 较高的HEI-2015分数与女性DOR几率在调整混因素后下降31%有关.
科学领域:
- 生殖内分泌学和营养科学.
背景情况:
- 卵巢储备减少 (DOR) 显著影响女性的生育能力和生殖成功.
- 饮食模式和DOR风险之间的关系仍未得到充分研究.
研究的目的:
- 调查2015年健康饮食指数 (HEI-2015) 的遵守与发展DOR的风险之间的关联.
主要方法:
- 一项涉及370名伊朗妇女 (120名DOR,250名对照) 的病例控制研究.
- 采用半定量食品频率调查问卷收集的饮食数据.
- 对HEI-2015分数和多变量后勤回归的分析,以评估与DOR风险的关联.
主要成果:
- 在未经调整的模型中没有发现任何显著的关联 (OR 0.78;95%CI 0.59,1.03).
- 在对身体活动和能量摄入进行调整后,HEI-2015得分的最高四分位数显示DOR的几率减少了31% (OR 0.69;95%CI 0.46,0.93).
- 考虑到所有潜在的混因素后,这种关联仍然很重要.
结论:
- 增加对HEI-2015饮食模式的坚持可能会显著降低卵巢储备减少的风险.
- 需要进一步的前性研究和临床试验来验证这些发现.
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