在甲状腺相关轨道病的轨道减压后角膜的生物机械变化,用Corvis ST测量
Mahdi Soleymanzadeh1, Seyed Mohsen Rafizadeh2, Ghazal Ghochani1
1Department of Oculo-Facial Plastic and Reconstructive Surgery, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, 1336616351, Iran.
Scientific reports
|July 23, 2024
概括
在甲状腺眼病 (TED) 患者的轨道减压手术改变了眼睛的生物力学. 关键参数如第二次平整时间 (A2T) 和最高腔 (HC) 变化,表明角膜度可能会降低,需要推迟折射手术.
科学领域:
- 眼科医生 眼科 眼科
- 眼部生物力学 眼部生物力学
- 外科手术的结果
背景情况:
- 甲状腺眼病 (TED) 可以导致显著的眼部形和视力损伤.
- 轨道减压手术是TED常见的治疗方法,以缓解轨道内压力.
- 手术后的眼部生物力学变化尚未完全理解.
研究的目的:
- 在非活动TED患者的轨道减压手术后,研究眼睛生物力学参数的动态变化.
- 为了评估角膜生物力学在术后期的时间演变.
- 为了将生物力学变化与手术结果相关联,并为未来的手术规划提供信息.
主要方法:
- 在31名患者 (46只眼睛) 的前性观察研究中,不活跃的TED患者经历了轨道减压.
- 在基线,1个月和3个月后进行的Corvis ST生物力学分析.
- 统计分析包括生物力学纠正眼内压 (bIOP) 的调整.
主要成果:
- 第二次平整时间 (A2T) 从基线显著增加到术后3个月 (P < 0.001).
- 第一次平面化速度 (A1V),最高孔腔 (HC) 峰距离,以及包度在1至3个月之间增加 (P ≤0.035).
- HC时间也从基线显著增加到3个月 (P = 0.027),而其他变化并不显著.
结论:
- 轨道减压手术在不活跃TED患者的眼睛生物力学参数中引发了显著的变化.
- 观察到的变化,特别是A2T和HC峰值距离的增加,可能表明角膜度降低.
- 解压后的角膜生物力学稳定是至关重要的;选择性角膜折断或眼内透镜植入手术应推迟.
更多相关视频
相关概念视频
01:28Angle Closure Glaucoma: Treatment
468
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
468
01:25Glaucoma: Overview
534
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
534
01:27Open Angle Glaucoma: Treatment
422
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
422