认知障碍患者的并发症指数与功能自主性之间的关联:系统性审查
M N Temedda1, A Garnier-Crussard, C Mouchoux
1Dr. Virginie Dauphinot, Clinical and Research Memory Center, Hôpital des Charpennes, 27 rue Gabriel Péri, 69100 Villeurbanne, France. Tel: +33 (0) 472432203. Fax: +33 (0) 472432054,
The journal of prevention of Alzheimer's disease
|July 24, 2024
概括
较高的并发症负担与认知障碍患者的功能自主性降低有关. 这种关系是动态的,需要纵向评估才能进行准确的测量.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 公共卫生 公共卫生
背景情况:
- 认知障碍影响功能自主.
- 伴随性疾病负担是健康结果的一个重要因素.
研究的目的:
- 系统地审查伴随性疾病负担与认知障碍患者功能自主性下降之间的关联.
- 探索这种关系的动态性质随着时间的推移.
主要方法:
- 系统审查PubMed/MEDLINE,ScienceDirect,Cochrane,以及Embase. 这三种类型的科学杂志.
- 纳入横截面和纵向研究,评估并发症指数和日常生活活动 (ADL).
- 使用NIH工具进行观察性研究的质量评估.
主要成果:
- 包括12项研究,其中3项是纵向研究.
- 横截面研究经常报告了显著的关联 (7项研究).
- 只有一个纵向研究发现了显著的关联,将并发症视为时间变化的共同变量.
结论:
- 较高的并发症指数与认知障碍的功能自主性较低有关.
- 这种关系是动态的,需要重复评估.
- 考虑时间变化的协变量的方法论方法对于准确的测量至关重要.
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