牙周病和阿尔茨海默氏症:从系统文献网络分析的见解
A Villar1, S Paladini, J Cossatis
1Alice Villar, Faculty of Medicine, University Castelo Branco (UCB), Brazil,
The journal of prevention of Alzheimer's disease
|July 24, 2024
概括
牙周病 (PD) 与阿尔茨海默氏症 (AD) 有关. 管理口腔健康可能有助于降低阿尔茨海默氏症的风险,尽管确切的原因需要进一步研究.
科学领域:
- 神经科学和口腔健康
- 系统的文学网络分析 (SLNA)
背景情况:
- 越来越多的证据表明口腔健康和神经退行性疾病之间存在联系.
- 牙周病 (PD) 是一种慢性炎症状况,影响牙和支骨.
研究的目的:
- 系统地分析牙周病 (PD) 和阿尔茨海默氏病 (AD) 之间的关系.
- 通过图书统计分析,确定这一领域的关键研究趋势和有影响力的研究.
主要方法:
- 进行了系统文献网络分析 (SLNA),结合了文献计量分析和系统文献评论 (SLR).
- 分析了2000年至2023年间发表的328篇论文,重点关注47篇最常被引用的论文.
- 使用了Bibliometrix R-package进行文献识别分析.
主要成果:
- 揭示了牙周病 (PD) 和阿尔茨海默氏病 (AD) 之间的正相关性.
- 确定了将PD与大脑炎症联系起来的两个主要途径:炎症级联和微生物参与.
- 强调口腔健康管理在潜在降低阿尔茨海默氏症风险方面的重要性.
结论:
- 管理牙周健康对于阿尔茨海默病的预防和治疗策略至关重要.
- 跨学科的方法对于调查和治疗神经退行性疾病,如阿尔茨海默氏症是必不可少的.
- 这项研究为未来在这一关键领域的研究提供了路线图.
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