相关实验视频
Updated: Jun 19, 2025

08:15
Polymeric Microneedle Array Fabrication by Photolithography
Published on: November 17, 2015
12.1K
[用西塔利普丁支持的快溶性聚合物微针的制备和性能评估]
Qinglong Xue1, Jian Zhuang1, Fengyi Liu1
1Institute of Plastic Machinery and Plastic Engineering (IPME), Beijing University of Chemical Technology, Beijing 100029, China.
概括
一种新型的快速溶解聚合物微针阵列补丁 (SGN-PVP/PVA-MN) 有效地为肥胖治疗提供西塔利普丁. 这个贴片显示药物释放速度快,并有效地穿透皮肤,提供了一个有前途的治疗选择.
科学领域:
- 制药科学 制药科学
- 生物材料工程 生物材料工程
- 药物输送系统 药物输送系统
相关概念视频
Dipeptidyl Peptidase 4 Inhibitors
180
Dipeptidyl peptidase 4 (DPP-4) is a serine protease widely distributed in the body. It's involved in the inactivation of GLP-1 and GIP hormones, which are crucial for insulin regulation. DPP-4 inhibitors, such as sitagliptin (Januvia), saxagliptin (Onglyza), linagliptin (Tradjenta), alogliptin (Nesina), and vildagliptin (Galvus), help increase the proportion of active GLP-1, enhancing insulin secretion. These inhibitors work by competitively binding to DPP-4. This binding causes a...
180
Factors Affecting Dissolution: Particle Size and Effective Surface Area
781
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
781

