在心血管疾病中的光学连贯性断层扫描的应用:文献计量和元分析
Wenjing Lian1, Cong Chen1, Jie Wang1
1Guang'anmen Hospital, China Academy of Chinese Medicine Sciences, Beijing, China.
Frontiers in cardiovascular medicine
|July 24, 2024
概括
光学连贯断层扫描 (OCT) 引导的皮肤冠状动脉干预 (PCI) 在随机对照试验中没有显著的益处. 然而,观察性研究表明,OCT指导的PCI可能会减少主要心脏不良事件 (MACE) 和目标损伤再血管化 (TLR).
科学领域:
- 心血管医学 心血管医学
- 医疗成像医学成像
- 干预心脏病学 干预心脏病学
背景情况:
- 光学连贯断层扫描 (OCT) 已经在二十年里推进了对血管内生物学的理解.
- 通过OCT识别罪祸首的病变可以彻底改变急性冠状动脉综合征 (ACS) 治疗.
- 图书统计分析和元分析对于评估CTD在心血管疾病和CTD指导的皮肤冠状动脉干预 (PCI) 中的作用至关重要.
研究的目的:
- 在心血管疾病领域对海外和海外国家和地区的研究进行文献分析.
- 进行元分析,比较OCT指导的PCI与血管学指导的PCI.
- 评估OCT在干预性心脏病学中的临床疗效和应用趋势.
主要方法:
- 采用了结合文献计量分析和元分析的双重方法.
- 2003年至2023年的文献从科学网络核心集合 (WoSCC) 中提取.
- 使用VOSviewer,CiteSpace和R进行文献计量分析;遵循PRISMA和AMSTAR指南进行RCT和观察性研究的元分析.
主要成果:
- 分析了310份出版物,显示年产量持续增加.
- 中国在出版物方面处于领先地位,而美国则表现出更大的研究影响力.
- 在11个RCT (n=5,277) 中,与血管学引导的PCI相比,OCT引导的PCI没有显著减少主要心脏不良事件 (MACE) 或其他不良结果.
- 然而,7项观察性研究 (n=4,514) 表明,OCT指导的PCI与降低的MACE和目标损伤再血管化 (TLR) 有关.
结论:
- 在OCT指导的PCI中,随机对照试验 (RCT) 没有显示出显著的临床益处.
- 从观察性研究中汇集的结果表明,在以OCT为指导的PCI中,MACE和TLR的潜在减少.
- 需要进一步的研究来澄清海洋和国外地区在PCI指导中的作用,特别是在特定的患者子组中.
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