相关实验视频

Updated: Jun 19, 2025

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates
06:10

Non-Viral Engineering of Primary Human T Cells via Homology-Mediated End-Joining Targeted Integration of Large DNA Templates

Published on: May 9, 2025

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电友性接近诱导合成适配器通过共同强制免疫受体信号传递来增强通用T细胞功能

Nickolas J Serniuck1,2,3, Eden Kapcan1,2,3, Duane Moogk1,2,4

  • 1Centre for Discovery in Cancer Research, McMaster University, Hamilton, ON, Canada.

Molecular therapy. Oncology
|July 24, 2024
PubMed
概括

协同免疫招募剂 (CIRs) 通过协同连接T细胞和瘤细胞来增强T细胞的抗瘤活性. 这种共价策略优于非共价方法,提高了免疫治疗的有效性.

关键词:
MT: 定期发行 定期发行化学/合成免疫疗法同价双功能适配器工程T细胞的工程T细胞.近距离诱导的标签是因为近距离.全球合成抗原受体

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