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Updated: Jun 19, 2025

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心脏输出量下降反映了Fontan完成后的循环损耗:连续心脏磁共振研究

Sara C Arrigoni¹, Rolf M F Berger², Tjark Ebels¹

¹Department of Cardiothoracic Surgery, University of Groningen, University Medical Center Groningen, Hanzeplein 1, PO Box 30.001, Groningen 9700 RB, The Netherlands.

European heart journal. Imaging methods and practice

|July 24, 2024

概括

随着时间的推移,Fontan患者的心脏磁共振 (CMR) 影像显示血液流量下降. 这种消耗与心室功能障碍无关,突出显示CMR.

科学领域:

心血管成像 - 心血管成像
儿童心脏病学儿童心脏病学
遗传性心脏病是一种先天性心脏病.

背景情况:

心脏磁共振 (CMR) 对Fontan患者的随访至关重要.
序列CMR在评估Fontan磨损中的作用尚不清楚.
源泉循环需要持续监测,以确保长期健康.

研究的目的:

为了前性地分析Fontan患者血液流量分布的依赖时间的演变.
用序列CMR评估心室体积和功能的变化.
了解串行CMR对评估Fontan磨损的贡献.

主要方法:

一项前性单中心研究,涉及88名Fontan患者和281次CMR检查 (2012-2022年).
分析血液流量分布,心室体积和喷射分数.
线性混合效应模型用于分析随着时间的推移重复的测量.

主要成果:

大动脉,马脉和肺动脉的索引流量在10年内显著下降.
平均指数化大动脉流量从3.03降至2.36 L/min/m2,但喷射分数保持稳定.
索引心室体积在连续CMR检查中没有显著变化.

结论:

连续CMR检测到的指数化大动脉和空腔肺流量减少反映了单静脉循环流失.
静脉缩功能障碍并不是这种观察到的磨损的主要原因.
常规序列CMR建议用于早期检测Fontan患者的显著变化.

关键词:

在Fontan流通的流通.心脏磁共振是一种心脏磁共振.遗传性心脏病是一种先天性心脏病.单胞体生理学单胞体生理学

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