种族和种族对动脉样硬化的影响:流行病学和危险因素
Yijun Huang1, Weihao Shi1, Qing He1
1Department of General Surgery, Huashan Hospital Affiliated to Fudan University, Shanghai, China.
SAGE open medicine
|July 24, 2024
概括
种族差异显著影响动脉狭窄,增加缺血性中风风险. 了解这些差异是制定针对不同族群的有针对性的预防和管理策略的关键.
科学领域:
- 血管医学 血管医学
- 流行病学 流行病学
- 遗传学 是一个遗传学.
背景情况:
- 冠状动脉样硬化相关的狭窄症,以冠状动脉斑块积累为特征,是缺血性中风的主要危险因素.
- 动脉狭窄的患病率和严重程度在不同种族和种族群体之间存在显著差异.
- 现有的研究突出了易感性和结果的差异,需要更深入地了解促成因素.
研究的目的:
- 审查和综合当前关于 Carotid 狭窄症的种族差异的知识.
- 为了识别动脉狭窄病理生理学和临床影响的种族特异性模式.
- 将风险因素分类,区分那些受种族影响的人与那些不受影响的人.
主要方法:
- 流行病学和比较成像研究的文献综述.
- 分析跨种族群体中关于中风风险和脑损伤发病率的数据.
- 基于其与种族差异相关的风险因素的分类.
主要成果:
- 美国原住民和白人更容易患上动脉狭窄症.
- 西班牙裔和黑人人口经历更严重的后果,包括增加脑损伤.
- 在中国人与白人群体中观察到明显的动脉狭窄模式.
结论:
- 种族差异显然影响了动脉狭窄的患病率,易感性和结果.
- 承认种族差异对于定制有效的预防,诊断和治疗策略至关重要.
- 解决这些差异对于减少缺血性中风的全球负担至关重要.
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