运动期间的生理反应在暴露于不理想妊娠环境的儿童中保持不变
Soraya Saidj1, Stephanie-May Ruchat2, Mélanie Henderson3,4,5
1School of Kinesiology and Physical Activity Sciences, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.
Obesity (Silver Spring, Md.)
|July 24, 2024
概括
非最佳妊娠因子 (SGFs) 在休息和运动期间没有改变儿童的机械效率或基质氧化. 这些发现表明,其他机制可能会导致与SGF暴露相关的肥胖风险增加.
科学领域:
- 儿科肥胖症研究的研究.
- 孕产妇和儿童的健康
- 人类生理学 人类生理学
背景情况:
- 非最佳妊娠因子 (SGFs) 与儿童肥胖风险增加有关.
- 这种关联背后的生理机制仍然不清楚.
- 研究机械效率 (ME) 和基板氧化提供了潜在的见解.
研究的目的:
- 为了确定SGF暴露是否影响儿童的ME和基质氧化.
- 探索将SGF与肥胖联系起来的潜在生理机制.
- 为了比较暴露和未暴露儿童之间的这些生理反应.
主要方法:
- 利用了来自北克肥胖和生活方式调查中的青少年队列的数据.
- 用最大循环测试和间接热量计来评估8-10岁的儿童.
- 在暴露于妊娠糖尿病,高血压疾病或母亲吸烟的儿童与未暴露儿童之间,在休息和运动期间测量ME和基质氧化.
主要成果:
- 在暴露和未暴露儿童之间在亚最大或最大运动期间,没有发现ME的显著差异.
- 基质氧化 (脂质和碳水化合物贡献) 在休息时或在次最大运动时没有差异.
- 这些生理参数在不同组中是相似的,无论SGF暴露程度如何.
结论:
- 暴露于研究的SGFs似乎不会改变儿童的ME或基质氧化.
- 研究的生理反应不能解释与SGFs相关的肥胖风险增加.
- 需要进一步的研究,以确定有助于SGF相关肥胖风险的替代机制.
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