早期和晚期发病之间的病因学和围产期结局非免疫hydrops fetalis胎儿
Seval Yılmaz Ergani1, Müjde Can İbanoğlu2, Ayberk Çakır2
1Etlik Zubeyde Hanım Women's Health Training and Research Hospital, Department of Perinatology - Ankara, Turkey.
概括
早期发病的非免疫性水胎儿 (NIHF) 通常会导致24周前的分娩. 晚期发病的NIHF显示出更高的活产率和心脏异常,表明这些疾病的管理需求不同.
科学领域:
- 周围生理学 周围生理学
- 胎儿医学 胎儿医学
- 遗传学 遗传学 是一个
背景情况:
- 非免疫性胎儿水 (NIHF) 是一种复杂的疾病,有多种不同的病因.
- 早期诊断和管理对于改善围产期结果至关重要.
研究的目的:
- 为了比较早期发病 (≤12周) 与晚发病 (>12周) 非免疫水胎儿的病因学和围产期结局.
- 为了确定与NIHF诊断的不同时间相关的不同特征和结果.
主要方法:
- 对42个非免疫性hydrops fetalis病例的回顾性审查.
- 早期和晚期发病组之间的诊断周,出生周,伴随异常和围产期结果的比较.
主要成果:
- 骨,中枢神经和胃肠系统的异常在早期发病的NIHF中更为常见.
- 心脏异常在晚期发病的NIHF (26.7%) 中更为普遍.
- 在出生周分布中观察到显著差异 (p=0.029),66.7%的早期发病病例在24周前分娩.
结论:
- 早期发病的NIHF经常与怀孕前24周内的分娩有关.
- 晚期发病的NIHF似乎有更高的活产率和更高的心脏异常发病率.
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