童年和青春期情绪变化的个人内生物机制
Yara J Toenders1,2,3, Marleen H M de Moor4, Renske van der Cruijsen5
1Developmental and Educational Psychology, Leiden University, Leiden, The Netherlands.
Human brain mapping
|July 24, 2024
概括
青少年的情绪变化增加,原因是丸激素和大脑连接的变化. 较高的丸激素预测了消极的情绪,而更强的vmPFC-杏仁体连接减少了情绪波动.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 内分泌学 在内分泌学.
背景情况:
- 情绪变化,或日常情绪波动,在青春期增加.
- 青春期及其相关的荷尔蒙和神经变化是这种青少年情绪变化的潜在驱动因素.
- 了解青少年情绪发展的生物学机制至关重要.
研究的目的:
- 研究青少年特有的情绪变化的内在变化的神经和荷尔蒙基础.
- 检查,皮质醇,青春期状态和休息状态功能性大脑连接的作用.
- 探索这些生物学因素与发育过程中的情绪变化和平均情绪之间的关系.
主要方法:
- 利用了两个纵向队列 (L-CID和莱登自我概念研究) 的数据.
- 收集了休息状态功能磁共振成像 (rs-fMRI) 和日常情绪数据.
- 采用随机拦截交叉滞后面板模型 (RI-CLPM) 来分析生物测量和情绪之间的个人内关系.
主要成果:
- 情绪变化和平均情绪在青春期达到顶峰,同时增加丸激素和自我报告的青春期.
- 在发育过程中,在前额叶皮层 (dlPFC,vmPFC) 和皮下区域 (caudate,杏仁体) 之间观察到功能连接性下降.
- 较高的丸激素预测了随后的平均负面情绪,而更强的vmPFC-杏仁体连接预测了情绪变化的下降.
结论:
- 大脑连接,特别是vmPFC-杏仁体通路,是影响青少年情绪发展的重要人体内生物机制.
- 水平与平均情绪有关,突出显示了荷尔蒙对青少年情绪状态的影响.
- 这些发现强调了神经生物学和荷尔蒙因素在塑造青少年情绪调节中的复杂相互作用.
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