在中国成年人中开发和验证饮食抑郁指数
Min Gao1,2, Jiali Zheng3, Fangyu Li4
1Center for Single-Cell Omics, School of Public Health, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.
Nutritional neuroscience
|July 24, 2024
概括
一个新的饮食抑郁指数 (DDI) 被开发和验证,以预测基于饮食的抑郁症. 发酵蔬菜和全谷物等特定食物与较低的抑郁风险有关,而大米和制蔬菜与更高的风险有关.
科学领域:
- 营养精神病学 营养精神病学
- 流行病学 流行病学
- 心理测量 心理测量 心理测量
背景情况:
- 饮食模式越来越多地被认为与心理健康有关,特别是抑郁症状.
- 需要一个经过验证的工具来量化不同人群中饮食和抑郁症之间的关系.
研究的目的:
- 开发和验证饮食抑郁指数 (DDI) 以预测中国大型癌症查队列中的抑郁症.
- 为了确定与抑郁症状相关的特定食物组.
主要方法:
- 在20个食品组中,DDI是从训练集 (n=2729) 中的食物频率调查问卷中开发的,使用减少的等级回归.
- 在一个验证集 (n=1176) 中,使用灵敏度,特异性和接收器运行特征分析来评估DDI的性能.
主要成果:
- DDI在预测抑郁症方面表现出良好的区分能力,总体AUC为0.799.
- 确定了DDI的最佳截止值,用于整个人口,男性和女性.
- 发酵蔬菜,新鲜蔬菜,全谷物和洋与抑郁症状的关系是相反的.
结论:
- 饮食抑郁指数 (DDI) 是一种验证的方法,用于评估饮食对抑郁症的影响.
- 特定的饮食成分,包括发酵蔬菜和全谷物,可能起到预防抑郁症的保护作用.
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