在手术前心声学衍生的平均dP/dTic预测了在接受中枢手术的儿童早期的术后功能障碍
Addison Gearhart1,2, Nikhil Thatte3,4, Sunakshi Bassi5,6
1Department of Cardiology, Boston Children's Hospital, 300 Longwood Ave, Boston, MA, 02115, USA. addisonsgearhart@gmail.com.
Pediatric cardiology
|July 24, 2024
概括
非侵入性平均dP/dtic测量预测儿科米特拉吐患者的术后心室功能. 这种回声心脏指数表明,在关节干预后评估缩功能具有前途.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
- 心脏外科手术 心脏外科手术
背景情况:
- 平均dP/dtic是心室功能的非侵入性心声测量.
- 在患有 mitrale regurgitation (MR) 的成年人中,平均dP/dtic预测了术后喷射分数 (EF).
- 它在患有MR的儿科先天性心脏病中的实用性未得到充分研究.
研究的目的:
- 为了评估发声心脏学衍生的平均dP/dtic在儿童MR患者的实用性.
- 为了将平均dP/dtic与其他指数比较,例如Tei指数和EF指数,用于评估心室功能在米特拉手术前后.
- 为了确定手术前的平均dP/dtic是否可以预测术后的缩功能.
主要方法:
- 对61名患有MR的儿科患者 (0-19岁) 进行了回顾性研究,这些患者接受了米特拉修复或更换 (2015-2021年).
- 包括平均dP/dtic,Tei指数和EF在内的心声数据是在手术前,手术后早期 (中位数6天) 和手术后晚期 (中位数350天) 收集的.
- 统计分析以比较心室功能指数,并评估手术前和术后测量之间的相关性.
主要成果:
- 中心干预与EF和平均dP/dtic的初始下降有关,随后恢复.
- 术前平均dP/dtic与早期和晚期术后EF显著相关.
- 术前EF与晚期术后EF相关,但与早期术后EF没有显著关系.
结论:
- 在患有MR的儿科患者中,非侵入性平均dP/dtic可能是术后心功能比EF更敏感的预测指标.
- 中心干预会影响缩功能,最初会下降,随后恢复.
- 平均dP/dtic在这个人群中为术前评估心室功能提供了潜在的优势.
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