亚洲肝移植的发展趋势
Ning Qi Pang1,2, Albert C Y Chan3, Alfred Wei Chieh Kow4,5,6
1Division of Hepatobiliary & Pancreatic Surgery, Department of Surgery, National University Hospital, National University Health System, NUHS Tower Block, 1E, Kent Ridge Road, Level 8, Singapore, 119228, Singapore.
Updates in surgery
|July 24, 2024
概括
亚洲的肝移植 (LT) 很早就开始,但面临着挑战. 活体供体肝移植 (LDLT) 和微创手术方面的创新现在正在推动该地区的进展.
科学领域:
- 肝病学和移植外科手术
- 器官移植研究 器官移植研究
- 亚洲医学史 亚洲医学史
背景情况:
- 亚洲的肝移植 (LT) 始于1964年,在全球开创性尝试后不久.
- 发展最初缓慢,原因是医疗保健的获取有限,公众意识和立法框架.
- 亚洲的各种社会文化因素影响了早期采用和进展.
研究的目的:
- 为了回顾亚洲肝移植的历史轨迹.
- 分析该地区LT的现状和挑战.
- 探索亚洲肝移植的未来趋势和创新.
主要方法:
- 亚洲肝移植里程碑的历史审查.
- 分析影响LT发展的因素,包括已故和活体捐赠.
- 检查手术技术的进步和捐赠者池的扩大.
主要成果:
- 尽管开始缓慢,但在一些亚洲国家,已故供体肝移植 (DDLT) 数量正在增加.
- 与高加索人相比,亚洲人器官捐献率较低,这一现象依然存在.
- 亚洲的中心开创了活体供体肝移植 (LDLT) 技术和微创手术.
结论:
- 死亡器官的有限供应刺激了LDLT的创新和亚洲的捐赠池扩张.
- 亚洲在捐赠者手术方面的专业知识正在为接受者推进最少的侵入性方法.
- 该地区有望在肝移植领域继续取得进展.
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