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Updated: Jun 19, 2025

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics
04:01

Author Spotlight: Tracing the Ferroptotic Signatures and Cell Death Dynamics in Medulloblastoma for Advanced Therapeutics

Published on: March 15, 2024

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通过调节铁化,LACTB可以抑制肝癌的进展

Kaixuan Zeng1, Na Huang2, Nanbin Liu3

  • 1Department of Geriatric Hepatobiliary, Pancreatic and Spleen Surgery, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China; National-Local Joint Engineering Research Center of Biodiagnosis & Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China; Tumor and Immunology Center of Precision Medicine Institute, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.

Redox biology
|July 24, 2024
PubMed
概括

血清蛋白β-乳糖酶样蛋白 (LACTB) 通过诱导依赖铁的细胞死亡 (铁死) 来抑制肝癌. LACTB针对HSPA8,影响ferritinophagy和关键的ferroptosis调节器,提供新的治疗途径.

关键词:
铁性化 (ferroptosis) 是一种据说,LACTB 是一个有趣的动物.伦瓦提尼布 (Lenvatinib) 是一种药物.肝癌是一种肝癌.

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