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Updated: May 13, 2026

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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Published on: January 13, 2017

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潜在的SARS-CoV-2 Mpro 类固醇抑制剂来自Aphanamixis polystachya (Wall. R. N. 帕克尔 (R. N. 帕克尔) 是一个著名的作家

Juan Ren1, Shi-Rui Fan2, Jieyun Cai3

  • 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, People's Republic of China; School of Life Sciences, Yunnan University, Kunming, Yunnan 650091, People's Republic of China; Research Unit of Chemical Biology of Natural Anti-Virus Products, Chinese Academy of Medical Sciences, Beijing 100730, China.

Fitoterapia
|July 24, 2024
PubMed
概括

从Aphanamixis polystachya中分离出来的六种新类固醇显示出对SARS-CoV-2主要蛋白酶的抑制活性. 这些化合物有可能开发新的抗病毒疗法来治疗严重急性呼吸综合征冠状病毒2.

关键词:
阿法纳米克西斯是多元化的.在SARS-CoV-2 M (((pro) 中.这是一种类固醇.

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