急性肌酸补充剂对老年男性心脏和血管反应的影响;一个随机对照试验
Adrian Aron1, Eryn J Landrum1, Adam D Schneider1
1Department of Physical Therapy, Waldron College of Health and Human Services, Radford University, Radford, VA, USA.
短期补充肌酸可以改善老年人的血管健康,减少动脉硬,并可能有助于心血管疾病管理. 这项研究强调了肌酸.
科学领域:
- 心血管健康 心血管健康
- 营养科学 营养科学
- 老年学是一门学科.
背景情况:
- 肌酸在神经退行性疾病,肌肉病变和缩症方面表现有前途.
- 心血管疾病 (CVD) 可能受益于肌酸,因为它对炎症,高血糖和脂质失调的影响.
- 研究肌酸对老年人心脏和血管健康的影响至关重要.
研究的目的:
- 评估短期肌酸补充对老年人心脏和血管健康的影响.
- 为了确定肌酸补充是否会影响心血管疾病的风险因素.
- 评估动脉硬度和心脏功能的变化.
主要方法:
- 年长的男性 (55-80岁) 被随机分为肌酸,安慰剂和对照组.
- 补充包括每天20克克reatine或安慰剂7天.
- 血管反应通过动脉脉冲波速度测量,心脏功能通过阻抗心脏学测量.
主要成果:
- 肌酸组显示心血管指数显著改善 (p=0.03).
- 在肌酸组中观察到一个非显著的趋势,即缩短了上升的时间和缩血压.
- 心脏功能参数 (中风体积,收缩率,喷射率) 在各组之间没有显著差异.
结论:
- 在老年人中,急性肌酸补充对血管参数产生积极影响,特别是动脉硬和动脉样硬化.
- 肌酸补充显示了作为辅助疗法的潜力,用于管理老年人的心血管疾病.
- 需要进一步的研究来探索肌酸对心血管的长期益处.
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