脂肪酸结合的EPI-X4衍生物具有增加的活性和体内稳定性

Mirja Harms1, André Haase2, Armando Rodríguez-Alfonso3

  • 1Institute of Molecular Virology, Ulm University Medical Center, Ulm 89081, Germany.

概括

用脂肪酸优化的EPI-X4变体显示出增强的CXCR4对抗性和稳定性. 这些脂显示出涉及CXCL12/CXCR4轴的疾病的治疗潜力.

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