2017年至2023年间,口腔健康领域公布的RCT数据共享和透明度指标
Filippos Mikelis1, Dimitra Karamalaki2, Aikaterini Mikeli3
1Department of Orthodontics, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
Journal of dentistry
|July 24, 2024
概括
关于口腔健康随机对照试验 (RCT) 数据共享的报告非常低. 提高RCT的透明度对于研究的可重复性和可信度至关重要.
科学领域:
- 口腔健康研究研究 口腔健康研究
- 生物医学科学 生物医学科学
- 临床试验 临床试验
背景情况:
- 数据共享和透明度在科学研究中越来越重要.
- 在牙科随机对照试验 (RCT) 中评估数据共享实践对于评估研究完整性至关重要.
- 之前的研究已经强调了跨医学学科的数据共享报告的变化.
研究的目的:
- 确定牙科RCT中初级数据和统计代码的数据共享报告的比例.
- 检查数据共享实践与期刊,出版和结果特征之间的关联.
- 评估牙科RCT中的注册和融资声明等透明度指标.
主要方法:
- 2017年至2023年间发表在12个高影响力牙科期刊的六个专业领域的RCT的系统审查.
- 主要结果:RCT报告有意共享或公开共享初级数据的比例.
- 二次结果:检查统计代码共享,资金,注册和具有研究特征的关联.
主要成果:
- 总共分析了752个RCT;只有15.8%的人报告了数据共享意向或开放数据.
- 只有在一项研究中报告了统计代码共享.
- 牙周病学 (27.1%) 和正牙科 (22.3%) 的RCT显示数据共享意向的比率更高.
- 已注册的RCT报告数据共享意向的几率明显高 (2.04倍) (p=0.03).
- 年份,牙科领域和作者大陆显著影响了数据共享实践 (p < 0.001).
结论:
- 口腔健康RCT显示数据共享实践的流行率非常低.
- 需要提高牙科研究的透明度,以提高可复制性和可信度.
- 促进数据共享对于基于可靠证据的强有力的临床决策至关重要.
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