在阿根廷首次报告了马匹帕维病毒肝炎 (EqPV-H)
C Olguin-Perglione1, R Politzki1, I Alvarez1
1Laboratorio de Virus Adventicios, Instituto de Virología e Innovaciones Tecnológicas (IVIT), INTA-CONICET, Nicolás Repetto y De los Reseros (s/n), Hurlingham, Buenos Aires CP1686, Argentina.
Veterinary journal (London, England : 1997)
|July 24, 2024
概括
在阿根廷的商业马血清和个人供体马中检测到马类帕尔沃病毒-肝炎 (EqPV-H) DNA,突出了马类生物产品生物安全的需要. 这一发现对于了解EqPV-H传播风险至关重要.
科学领域:
- 兽医病毒学 兽医病毒学
- 马类传染病 马类传染病
背景情况:
- 马类帕尔沃病毒肝炎 (EqPV-H) 越来越多地被认为是导致马类泰勒病的原因.
- 以前的报道表明,EqPV-H只在南美洲的巴西存在.
研究的目的:
- 调查阿根廷马匹血清样本和商业血清批次中EqPV-H DNA的流行情况.
- 对检测到的EqPV-H分离物进行遗传学分析.
主要方法:
- 量化聚合酶连锁反应 (qPCR) 用于初始的EqPV-H DNA检测.
- 采用NS1嵌套PCR来确认和基因分析阳性或不确定的样本.
- 分析包括血清池,商业血清批量和个人供体马血清.
主要成果:
- 在15.7%的血清池中检测到EqPV-HDNA (通过嵌套PCR确认的不确定的结果).
- 在商用马血清批量中,很大一部分 (60%) 检测出了EqPV-H DNA.
- 在1.71%的单个捐赠马血清中发现了EqPV-H DNA,基因分析显示与国际隔离物相似.
结论:
- 这项研究提供了在阿根廷出现EqPV-H的第一个证据,影响了个人马和商业血清产品.
- 这些发现强调了严格的生物安全措施对于商用马类血清和血源产品的关键重要性,以防止病毒传播.
相关概念视频
Rocky Mountain Spotted Fever
Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Poliomyelitis
Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Arboviral Encephalitis
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Hepatitis
Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...


