改善囊内镜可视化和诊断产量的准备方案 (PrepRICE):一个多中心随机试验
Maria Manuela Estevinho1, Mara Sarmento Costa2, Rita Franco3
1Department of Gastroenterology, Centro Hospitalar Vila Nova de Gaia Espinho, Vila Nova de Gaia, Portugal; Department of Biomedicine, Unit of Pharmacology and Therapeutics, Faculty of Medicine, University of Porto, Porto, Portugal.
Gastrointestinal endoscopy
|July 24, 2024
概括
对于小肠囊内镜 (SBCE) 的程序内肠道准备,与传统的夜前治疗方案相比,显著改善了可视化和诊断产量. 在囊摄入后服用的G4疗法是患者最能容忍的.
科学领域:
- 胃肠病学 胃肠病学
- 内镜检查是指内镜检查.
- 诊断成像 诊断成像 诊断成像
背景情况:
- 目前的指导方针建议在小肠囊内镜 (SBCE) 之前进行肠道准备.
- 肠道准备的最佳时间和方案仍未确定.
- 本研究解决了在SBCE中需要基于证据的准备协议的需求.
研究的目的:
- 为了比较四种不同的SBCE净化疗法的疗效.
- 评估准备时间对小肠可视化质量 (SBVQ) 和诊断产量 (DY) 的影响.
- 评估患者报告的结果和不同SBCE准备方案的耐受性.
主要方法:
- 一项前性,随机的多中心研究,涉及387名疑似小肠出血的患者.
- 他们比较了四种清洗疗法:前一天晚上 (G1),第二天早上 (G2),分剂量 (G3) 和程序内 (G4).
- 对于每种疗法,评估了SBVQ (Brotz分数),DY,传输时间和患者耐受性.
主要成果:
- 与G1和G2相比,程序内清洁疗法 (G3和G4) 显著改善了SBVQ和DY.
- 接受程序内清洗剂的患者显示了更短的小肠传输时间和更高的血管疏通症检测率.
- 在囊摄入后完全服用G4疗法,表现出优异的患者满意度和耐受性.
结论:
- 在手术 (手术内) 期间使用的肠道制备剂可提高SBCE的可视化和诊断产量.
- 传统的夜前准备与较差的结果有关.
- 推G4疗法是因为它的有效性和最佳患者耐受性.
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