在下大脑下出血后脑血管的危险因素:观察性研究的系统审查
Abdullah Tawakul1, Majed Mohammedali Alluqmani2, Ahmad Salim Badawi3
1Department of Medicine, Faculty of Medicine, Umm Al-Qura University, Makkah, Saudi Arabia.
Neurocritical care
|July 24, 2024
概括
在下大脑下出血后的大脑血管是常见的. 关键的危险因素包括年轻的年龄,女性性别,吸烟,酒精和某些疾病. 白血细胞症是显著的预测因素.
科学领域:
- 神经学 神经学
- 关键护理医学 关键护理医学
- 流行病学 流行病学
背景情况:
- 脑血管 (CV) 随着下关节出血 (SAH) 显著导致患者的死亡率和不良的神经结果.
- 识别CV风险因素对于制定有效的预防和治疗策略至关重要.
研究的目的:
- 系统地审查和综合有关大脑血管发育的风险因素的证据,在成年患者下arachnoid出血.
主要方法:
- 在五个主要数据库 (PubMed, EBSCO, Web of Science, Science Direct, Google Scholar) 进行了广泛的文献搜索,以进行分析观察研究.
- 包括2016年1月1日至2023年8月9日期间发表的研究,并使用纽卡斯尔-太华规模评估偏差风险.
- 总共分析了33项涉及24,958名SAH患者的研究.
主要成果:
- CV 的总发病率为 27.1% (6,761 在 24,958 个患者中).
- 已确定的危险因素包括年龄较小,女性性别,吸烟,酒精消费,更高的修改费舍尔等级 (3-4),升高的亨特和赫斯等级,以及糖尿病,高血压,心力衰竭和以前的中风等并发症.
- 白血细胞症一直被确定为CV的显著预测因素.
结论:
- 本综述总结了SAH后心血管风险因素的当前数据,突出了已确定的预测因素,并确定了需要进一步调查的领域.
- 诸如动脉曲,电解质失衡,贫血和特定麻醉剂等因素需要进行额外的研究来验证.
- 较大的观察性研究和临床试验对于确认显著预测因素和改善SAH患者结果至关重要.
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