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Updated: Jun 19, 2025

Targeted DNA Methylation Analysis by Next-generation Sequencing
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CpG甲基化和基因表达之间的相关性是由序列变异驱动的

Olafur Andri Stefansson1, Brynja Dogg Sigurpalsdottir2,3, Solvi Rognvaldsson2

  • 1deCODE genetics/Amgen Inc., Reykjavik, Iceland. olafurs@decode.is.

Nature genetics
|July 24, 2024
PubMed
概括

在CpG位点中的DNA甲基化模式调节基因表达. 由DNA序列变异驱动的基因特异甲基化定量特征位点 (ASM-QTLs) 解释了基因表达和CpG甲基化之间的大部分联系.

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