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Updated: Jun 19, 2025

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通过消除早期内体标志物RAB5A中的CTCF/PRC2诱导的抑制,CircARAP2控制sMICA诱导的NK细胞脱敏

Feifei Guo1, Nawen Du1, Xue Wen1

  • 1Cancer Center, The First Hospital of Jilin University, 71 Xinmin Street, Changchun, 130021, China.

Cellular and molecular life sciences : CMLS
|July 24, 2024
PubMed
概括

循环RNA circARAP2通过促进NKG2D内细胞分裂来驱动NK细胞脱敏. 抑制circARAP2可以缓解这种脱敏,为瘤免疫逃避提供了一个新的治疗标.

关键词:
细胞内存症是指细胞内存症.希斯甲基化 希斯甲基化在NK细胞脱敏感化过程中.在NKG2D中,它是NKG2D.环RNA 环RNA 是一个环RNA.这就是SMICA.

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