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Updated: Jun 19, 2025

Measurement of Protein Turnover Rates in Senescent and Non-Dividing Cultured Cells with Metabolic Labeling and Mass Spectrometry
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跨平台蛋白质组学极端老年人的签名

Eric R Reed1, Kevin B Chandler2,3, Prisma Lopez4

  • 1Data Intensive Study Center, Tufts University, Boston, MA, USA.

GeroScience
|July 24, 2024
PubMed
概括

我们确定了80种与极端老年相关的血清蛋白质,验证了之前的发现,并突出了血液凝结和IGF信号传递在衰老中的途径. 这种签名有助于区分百岁老人与年轻人.

关键词:
极端的长寿 极端的长寿质谱测量质量谱测量血清蛋白质组学 血清蛋白质组学在 SomaLogic 找 索马逻辑

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相关概念视频

Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
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